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. 2021 May 25;46(10):1788–1801. doi: 10.1038/s41386-021-01023-4

Table 1.

(a) SMR and (b) S-TissueXcan gene sets associated with cognitive function. Only novel results are displayed.

Gene sets Gene Set P Gene set categories
(a) SMR
GOBP:regulation_of_binding 8.54E−06 Cell binding
REACTOME:Signaling_by_Rho_GTPases 2.28E−06 Cell metabolism
GOBP:small_GTPase_mediated_signal_transduction 2.13E−05 Cell metabolism
REACTOME:Signaling_by_Rho_GTPases 3.05E−07 Cell metabolism
GOBP:nucleosome_organization 5.92E−06 Cell structure
GOBP:protein-DNA_complex_assembly 1.81E−06 Cell structure
GOBP:protein-DNA_complex_subunit_organization 2.17E−07 Cell structure
GOBP:cell-substrate_adhesion 5.06E−06 Cell structure
GOBP:response_to_glucose 4.80E−06 Interaction with small molecules
GOBP:response_to_hexose 3.73E−06 Interaction with small molecules
GOBP:response_to_monosaccharide 8.65E−06 Interaction with small molecules
GOBP:macromolecule_methylation 4.62E−08 Methylation
GOBP:methylation 3.29E−07 Methylation
REACTOME:Ion_channel_transport 1.00E−05 Neuronal/Dendritic regulation/development
(b) S-TissueXcan
GOMF:actin_binding 6.44E−06 Cell binding
GOMF:chromatin_binding 4.52E−06 Cell binding
GOBP:cellular_macromolecular_complex_assembly 1.71E−07 Cell structure
GOBP:cellular_protein_complex_assembly 1.68E−07 Cell structure
GOBP:cellular_response_to_interferon-gamma 2.67E−06 Interaction with small molecules