Table 1.
UnkcKO mice are born at expected Mendelian ratios.
| Genotype | Observed | Expected | Frequency observed (%) | Frequency expected (%) |
|---|---|---|---|---|
| Control (Unktm1c/tm1c) | 69 | 64.5 | 26.74 | 25 |
| Control (Unktm1c/+) | 58 | 64.5 | 22.48 | 25 |
| UnkcKO heterozygous (Nestin Cre, Unktm1d/+) | 77 | 64.5 | 29.84 | 25 |
| UnkcKO homozygous (Nestin Cre, Unktm1d/tm1d) | 54 | 64.5 | 20.93 | 25 |
| Total | 258 | 258 | 100 | 100 |
The table shows the number of pups born for each genotype, from 32 litters. Statistical significance was calculated with Pearson’s Chi-square test, Chi-square value = 5.1, p = 0.165.