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. 2021 Aug 11;11:16274. doi: 10.1038/s41598-021-95904-9

Table 1.

Demographic and clinical characteristics of patients with pachychoroid neovasculopathy.

Number of patients 99
Number of eyes 100
Age (years) 67.5 ± 10.5
Male 78 (78.8%)
Choriocapillaris filling delay 100 (100%)
Overlap of filling delay area and dilated vortex vein region (Grade: eyes)

Grade 3: 58 (58.0%)

Grade 2: 37 (37.0%)

Grade 1: 5 (5.0%)

Grade 0: 0

CVH 63 (63.0%)
Overlap of CVH area and dilated vortex vein region (Grade: eyes)

Grade 3: 45 (71.4%)

Grade 2: 17 (27.0%)

Grade 1: 1 (1.6%)

Grade 0: 0

CNV within the filling delay area 100 (100%)
RPE atrophy 71 (71.0%)
RPE atrophy within the filling delay area 68 (95.8%)
Central choroidal thickness (µm) 309 ± 97
Central choroidal thickness in eyes with CVH (µm) 326 ± 98 P = 0.017
Central choroidal thickness in eyes without CVH (µm) 280 ± 88
Vortex vein anastomosis in ICGA images 67 (67.0%) P < 0.001
Vortex vein anastomosis in en face OCT images 97 (97.0%)

CVH choroidal vascular hyperpermeability, RPE retinal pigment epithelium, CNV choroidal neovascularization, ICGA indocyanine green angiography, OCT optical coherence tomography.

Grade 3: filling delay or CVH area is entirely involved in the dilated vortex vein region.

Grade 2: 50% or more of filling delay or CVH area overlaps with the dilated vortex vein region.

Grade 1: less than 50% of filling delay or CVH area overlaps with the dilated vortex vein region.

Grade 0: no tendency for overlapping between filling delay or CVH area and dilated vortex vein region.