TABLE 3.
Hazard ratiosa (95% CI) for CKD by weekly working hours in clinically relevant subgroups
| Subgroup | Weekly working hours | P for interaction | ||
|---|---|---|---|---|
| 35‐40 | 41‐52 | >52 | ||
| Age | ||||
| <40 years (n = 68 215) | 1.00 (reference) | 0.96 (0.41‐2.24) | 1.36 (0.56‐3.28) | .465 |
| ≥40 years (n = 29 641) | 1.00 (reference) | 1.66 (0.96‐2.87) | 2.06 (1.14‐3.71) | |
| Sex | ||||
| Women (n = 24 166) | 1.00 (reference) | 0.74 (0.17‐3.26) | 2.15 (0.49‐9.45) | .571 |
| Men (n = 73 690) | 1.00 (reference) | 1.59 (0.97‐2.62) | 2.04 (1.21‐3.44) | |
| BMI | ||||
| <25 kg/m2 (n = 67 569) | 1.00 (reference) | 1.22 (0.66‐2.22) | 1.84 (0.98‐3.48) | .549 |
| ≥25 kg/m2 (n = 30 287) | 1.00 (reference) | 1.97 (0.95‐4.11) | 2.24 (1.03‐4.86) | |
Abbreviations: BMI, body mass index; CI, confidence interval; CKD, chronic kidney disease; HOMA‐IR, homeostasis model assessment of insulin resistance; hsCRP, high‐sensitivity C‐reactive protein; KOSS‐SF, Korean Occupational Stress Scale‐Short Form.
a
Estimated from Cox proportional hazard models adjusted for age, sex, year of screening examination, center, alcohol intake, smoking status, regular exercise, education level, history of dyslipidemia, medication for dyslipidemia, BMI, systolic blood pressure, fasting blood glucose, HOMA‐IR, uric acid, hsCRP, work shift schedule, and total KOSS‐SF score.