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. 2021 Aug 11;11:16343. doi: 10.1038/s41598-021-95835-5

Table 4.

Univariate analysis of clinicopathological variables associated with overall survival.

Variable Before PSM After PSM
n 5-year OS (%) P n 5-year OS (%) P
Age, years 0.285 0.261
≤ 60 697 61.3 411 62.6
> 60 116 53.8 59 52.9
Gender 0.907 0.874
Male 717 60.7 414 61.2
Female 96 57.2 56 61.8
Etiology 0.380 0.288
Hepatitis B/C 751 59.7 441 60.8
Other 62 66.1 29 67.7
Alanine aminotransferase, U/L 0.678 0.724
≤ 40 509 59.3 275 59.3
> 40 304 61.4 195 63.6
Portal hypertension  < 0.001  < 0.001
Absent 579 68.2 345 69.9
Present 234 40.8 125 37.4
Child–Pugh grade  < 0.001 0.001
A 764 60.8 453 62.4
B 49 51.0 17 37.6
AFP, ng/mL  < 0.001 0.031
≤ 400 521 65.8 278 67.1
> 400 292 50.1 192 52.7
Tumor size, cm 0.002 0.027
≤ 5 464 61.5 235 62.8
> 5 349 59.9 235 60.2
Extent of hepatectomy 0.081 0.067
Minor hepatectomy 713 60.6 460 61.7
Major hepatectomy 100 60.2 10 31.1
Intraoperative blood transfusion 0.001 0.012
No 662 62.4 393 63.7
Yes 151 50.2 77 47.9
Histological severity of cirrhosis  < 0.001  < 0.001
Mild cirrhosis 376 73.0 230 73.4
Moderate/severe cirrhosis 437 48.1 240 49.4
Microvascular invasion  < 0.001 0.028
Absent 675 62.3 382 63.8
Present 138 48.6 88 48.2
Tumor differentiation  < 0.001  < 0.001
Well 179 76.9 83 79.1
Moderate/poor 634 55.2 387 57.5

PSM propensity score matching, OS overall survival, AFP alpha-fetoprotein.