Table 4.
Variable | Before PSM | After PSM | ||||
---|---|---|---|---|---|---|
n | 5-year OS (%) | P | n | 5-year OS (%) | P | |
Age, years | 0.285 | 0.261 | ||||
≤ 60 | 697 | 61.3 | 411 | 62.6 | ||
> 60 | 116 | 53.8 | 59 | 52.9 | ||
Gender | 0.907 | 0.874 | ||||
Male | 717 | 60.7 | 414 | 61.2 | ||
Female | 96 | 57.2 | 56 | 61.8 | ||
Etiology | 0.380 | 0.288 | ||||
Hepatitis B/C | 751 | 59.7 | 441 | 60.8 | ||
Other | 62 | 66.1 | 29 | 67.7 | ||
Alanine aminotransferase, U/L | 0.678 | 0.724 | ||||
≤ 40 | 509 | 59.3 | 275 | 59.3 | ||
> 40 | 304 | 61.4 | 195 | 63.6 | ||
Portal hypertension | < 0.001 | < 0.001 | ||||
Absent | 579 | 68.2 | 345 | 69.9 | ||
Present | 234 | 40.8 | 125 | 37.4 | ||
Child–Pugh grade | < 0.001 | 0.001 | ||||
A | 764 | 60.8 | 453 | 62.4 | ||
B | 49 | 51.0 | 17 | 37.6 | ||
AFP, ng/mL | < 0.001 | 0.031 | ||||
≤ 400 | 521 | 65.8 | 278 | 67.1 | ||
> 400 | 292 | 50.1 | 192 | 52.7 | ||
Tumor size, cm | 0.002 | 0.027 | ||||
≤ 5 | 464 | 61.5 | 235 | 62.8 | ||
> 5 | 349 | 59.9 | 235 | 60.2 | ||
Extent of hepatectomy | 0.081 | 0.067 | ||||
Minor hepatectomy | 713 | 60.6 | 460 | 61.7 | ||
Major hepatectomy | 100 | 60.2 | 10 | 31.1 | ||
Intraoperative blood transfusion | 0.001 | 0.012 | ||||
No | 662 | 62.4 | 393 | 63.7 | ||
Yes | 151 | 50.2 | 77 | 47.9 | ||
Histological severity of cirrhosis | < 0.001 | < 0.001 | ||||
Mild cirrhosis | 376 | 73.0 | 230 | 73.4 | ||
Moderate/severe cirrhosis | 437 | 48.1 | 240 | 49.4 | ||
Microvascular invasion | < 0.001 | 0.028 | ||||
Absent | 675 | 62.3 | 382 | 63.8 | ||
Present | 138 | 48.6 | 88 | 48.2 | ||
Tumor differentiation | < 0.001 | < 0.001 | ||||
Well | 179 | 76.9 | 83 | 79.1 | ||
Moderate/poor | 634 | 55.2 | 387 | 57.5 |
PSM propensity score matching, OS overall survival, AFP alpha-fetoprotein.