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. 2021 Aug 11;11:16362. doi: 10.1038/s41598-021-95827-5

Figure 4.

Figure 4

Effects of metformin on autophagy and autolysosome in DN kidneys. Autolysosomes were detected by transmission electron microscope at the 4-week molding (a) or 12-week molding (b). The blue arrow indicates autophagy, and the red arrow indicates autolysosome. Scale bar represents 5 μm (left) and 1 μm (right) respectively. 4W: 4-week; 12W: 12-week; Met: metformin.