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. 2021 Aug 11;11:16313. doi: 10.1038/s41598-021-95659-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differential microbiota composition of the fecal specimen from the cage change group. (a) PCA and (b) PCoA plot of fecal microbiota. (c) Cladogram from linear discriminant analysis effect size (LEfSE) and enriched taxonomy in either the control or PS150 group are colored red and green, respectively. (d) LDA score from LEfSE analysis. (e) The stacked plot of relative microbial distribution at the order level.