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. 2021 Aug 11;11:16293. doi: 10.1038/s41598-021-95771-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Body weight curve and survival condition of mice infected with different doses of H7N9/PR8 recombinant viruses. Body weight change and survival condition of C57BL/6 mice (n = 5/group) inoculated intranasal with 10¹–10⁶ TCID₅₀ recombinant H7N9/PR8 viruses. Control group: PBS. (A) 10¹ TCID₅₀; (B) 10² TCID₅₀; (C) 10³ TCID₅₀; (D) 10⁴ TCID₅₀; (E) 10⁵ TCID₅₀; (F) 10⁶ TCID₅₀.