FIGURE 9.

Photothermal treatment of cervical cancer. (A) FPS-PVP NSs are used in the synergistic treatment of cancer chemodynamic therapy and PTT in the NIR-Ⅱ. The illustration is the bat model of FPS. (B) UV-vis-NIR absorbance spectra of FPS-PVP NSs at different Fe concentrations (3, 6, 12, and 24 μg ml⁻¹). (C) Growth curves of mouse tumors at 12 days after different treatments (n = 5). (D) The survival rate of mice after 12 days of different treatments (reproduced from (Zhang et al., 2020) with permission from Wiley-VCH Verlag). (E) Schematic diagram of DPP-ⅡD-FA nanoparticles for photothermal treatment of superficial tumors. (F) Absorption spectrum of DPP-ⅡD-FA nanoparticles dispersed in PBS. (G) Ex vivo fluorescence image of mouse main organs 24 h after DPP-ⅡD-FA nanoparticle injection. (H) Relative tumor volumes after various treatments (reproduced from (Wei et al., 2018) with permission from Royal Society of Chemistry). (I) Application of TBDOPV-DT NPs in PTT in vivo. (J) Absorption spectra and picture (inset) of TBDOPV-DT NPs (water, right) and TBDOPV-DT (THF, left). (K) The whole-body IR images of mice after injection of TBDOPV-DT NPs intratumorally (0.56 mg kg⁻¹) and irradiated by 1,064 nm laser (0.90 W cm⁻²) or intravenously (1.94 mg kg⁻¹) and irradiated by laser (1.30 W cm⁻²) (reproduced from (Sun et al., 2018) with permission from American Chemical Society).