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. 2021 Jul 29;12:673103. doi: 10.3389/fphar.2021.673103

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Copyright © 2021 Shoaib, Tufail, Sherwani, Yusuf and Islam.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of PEITC on apoptosis induction as assessed by caspase-3, -8 and -9 activity assays. (A-C) PEITC-treatment (20, 25 and 30 μM) resulted in induction of apoptosis in CaSki cells through activation of caspase-3, -8 and -9 after 24 h. (D) Combined graph exhibiting activation of various cellular caspases in cervical cancer cells after PEITC-treatment. The data represents mean ±SD of three independent experiments. *p value < 0.05 compared with the untreated control was considered statistically significant.