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. 2021 Jul 29;12:673103. doi: 10.3389/fphar.2021.673103

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Copyright © 2021 Shoaib, Tufail, Sherwani, Yusuf and Islam.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of PEITC on activation of caspases in CaSki cells as assessed in the presence of caspase inhibitors. Percent cell viability of PEITC-treated (20, 25 and 30 μM) CaSki cell was determined in the presence of caspase inhibitors by MTT assay. (A) Z-DEVD-FMK-caspase-3 inhibitor, (B) Z-IETD-FMK-caspase-8 inhibitor and (C) Z-LEHD-FMK-caspase-9 inhibitor. (D) Combined graph showing percent cell viability of PEITC-treated CaSki cells in the presence of caspase inhibitors. The data represents mean ±SD of three independent experiments. *p value < 0.05 compared with the untreated control was considered statistically significant.