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. 2021 Jul 29;12:673103. doi: 10.3389/fphar.2021.673103

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Copyright © 2021 Shoaib, Tufail, Sherwani, Yusuf and Islam.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of ROS generation using DC-FDA staining on CaSki cells treated with PEITC for 24 h and the images were captured by fluorescence microscopy. (A) PEITC treatment resulted in significant production of ROS in cervical cancer cells. (B) Percent cell viability of PEITC treated (20, 25 and 30 μM) CaSki cells was assessed in the presence of ROS inhibitor, NAC, by MTT assay. The data represents mean ±SD of three independent experiments. *p value < 0.05 compared with the untreated control was considered statistically significant.