Figure 3.

Pooled risk estimates for risk factors associated with the risk of premature MI. Pooled risk estimates include data with or without adjustment of cardiovascular risk factors. Given variability in the operational definition of risk factors across studies, risk factors were approximated to conventional definitions for inclusion in the meta-analysis (Supplemental Table 4, available online at http://www.mayoclinicproceedings.org). Details on study characteristics, risk factors, risk estimates by sex, and risk estimates by risk of bias are given in Supplemental Tables 4 to 15 and Supplemental Figures 1 to 14 (available online at http://www.mayoclinicproceedings.org). For family history of cardiac disease, diabetes mellitus, hypertension, dyslipidemia, and LDL cholesterol level, pooled risk estimates are based on the presence vs absence of the risk factor. Diabetes mellitus includes type 1 and/or type 2 diabetes. BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MI, myocardial infarction. SI conversion factor: To convert mg/dL values to mmol/L, multiply by 0.0259.