Table 3.

Diagnostic performance of clinical variables for the diagnosis of histoplasmosis

	Pancytopenia	< 50 CD4 cells/μL	AST levels > 46 IU/L	< 200 CD4 cells/μL	Elevated AST plus < 200 CD4 cells/μL	Pancytopenia plus < 50 CD4 cells/μL
Sensitivity	42	73.5	80	95.9	100	84
Specificity	88.5	59.1	50.5	15.7	11.7	57.4
Positive predictive value	60	43.4	40.9	32.6	32.1	44.7
Negative predictive value	78.8	84	85.5	90	100	89.7
Positive likelihood ratio	3.65	1.8	1.62	1.14	1.13	1.97
Negative likelihood ratio	0.66	0.45	0.4	0.26	0	0.28