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(A) Sialic acid- and Neu5Ac2en-derived inhibitors of SAs and (B) CMP-Neu5Ac-derived inhibitors of STs discussed in the text. Colours surrounding each compound represent the organism they inhibit (see key); note that compounds 6, 13, 14, and 15 inhibit more than one organism and so both representative colours are shown. Individual substituents on the Neu5Ac or Neu5ac2en ring are colour coded to highlight changes to the scaffold.
