Table 4.
Functional enrichment analysis.
Gene enrichment | Terms | Percent of genes (100%) | P value |
---|---|---|---|
Cellular component | Extracellular matrix | 13.33 | <0.001 |
Collagen type V | 4.00 | <0.001 | |
Mitochondrial respiratory chain complex I | 5.33 | <0.001 | |
Basement membrane | 4.00 | <0.001 | |
Extracellular space | 12.00 | <0.001 | |
Extracellular | 28.00 | <0.001 | |
Molecular function | Extracellular matrix structural constituent | 13.98 | <0.001 |
FAD binding | 1.08 | <0.01 | |
Oxidoreductase activity | 4.30 | <0.01 | |
Metallopeptidase activity | 3.23 | <0.05 | |
Immunoglobulin receptor activity | 1.08 | <0.05 | |
Transferase activity, transferring aldehyde or ketonic groups | 1.08 | <0.05 | |
Biological process | Metabolism | 21.51 | <0.001 |
Cell growth and/or maintenance | 16.13 | <0.001 | |
Energy pathways | 18.28 | <0.01 | |
Coenzyme and prosthetic group metabolism | 1.08 | <0.01 | |
Synaptic transmission | 1.08 | <0.05 | |
Mitochondrial transport | 1.08 | <0.05 | |
Biological pathway | Beta3 integrin cell surface interactions | 12.20 | <0.001 |
Epithelial-to-mesenchymal transition | 19.51 | <0.001 | |
coenzyme A biosynthesis | 4.88 | <0.001 | |
Respiratory electron transport | 9.76 | <0.01 | |
Vitamin B5 (pantothenate) metabolism | 4.88 | <0. 01 | |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
9.76 | <0. 01 |