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. 2021 Jul 29;12:709342. doi: 10.3389/fgene.2021.709342

TABLE 1.

Clinical parameters of 17 women subjects.

Clinical Pear subjects Apple subjects p-value
parameters (n = 7) (n = 10)
Adiposity markers
BMI (kg/m2) 27.4 ± 2.62 28.5 ± 3.74 0.58
Weight (kg) 73 ± 8.8 77 ± 11 0.55
Waist circumference (cm) 80.7 ± 6.03 94.4 ± 8.44 0.003
Hip circumference (cm) 108.1 ± 6.16 107.3 ± 10.5 0.81
Thigh circumference (cm) 60.2 ± 4.58 60.0 ± 5.06 > 0.9
Waist to hip ratio 0.75 ± 0.03 0.88 ± 0.04 < 0.0001
Total Fat mass (kg) 29.2 ± 6.65 33.8 ± 9.54 0.36
Total Lean mass (kg) 41.9 ± 5.4 40.6 ± 3.6 0.67
Fat Mass (%) 39.4 ± 6.5 43.2 ± 6.5 0.27
Android Fat mass (kg) 1.8 ± 0.7 2.9 ± 1.2 0.05
Gynoid Fat mass (kg) 5.8 ± 1.1 6.0 ± 1.8 > 0.9
Leg Fat Mass/Total FM 0.46 ± 0.05 0.36 ± 0.05 0.001
Circulating adiponectin (μg/mL) 13.0 ± 6.0 12.1 ± 5.4 0.87
VAT mass (g) 330 ± 296 724 ± 400 0.04
Liver fat (%) 2.0 ± 1.0 3.0 ± 2.0 0.53
IMAT (cm3) 253 ± 113 289 ± 106 0.53

Lipid profile

HDL (mg/dL) 63.1 ± 8.03 63.9 ± 15.2 0.87
LDL (mg/dL) 103 ± 17.5 110 ± 36.6 0.98
VLDL (mg/dL) 14.6 ± 7.72 17.6 ± 5.27 0.11
TGL (mg/dL) 72.3 ± 38.0 88.0 ± 26.2 0.13
Cholesterol (mg/dL) 181 ± 19.3 192 ± 38.2 0.86
Non-HDL chol (mg/dL) 117 ± 22.5 128 ± 38.4 0.87
Chol/HDL 2.93 ± 0.60 3.12 ± 0.78 0.65
LDL/HDL 1.64 ± 0.43 1.84 ± 0.70 0.55
FFA (μmol/L) 458 ± 178 482 ± 145 0.87

Glucose profile

Fasting Glucose (mg/dL) 85.1 ± 6.54 89.1 ± 5.97 0.29
Fasting Insulin [μ(iU)/mL] 6.53 ± 3.71 7.46 ± 3.00 0.40
HOMA-IR 1.38 ± 0.84 1.66 ± 0.72 0.47
HgbA1c (%) 5.33 ± 0.41 5.20 ± 0.24 0.40
C-peptide (ng/mL) 1.20 ± 0.40 1.30 ± 0.38 0.69

Metabolic markers/hormones

Age (years) 33 ± 8.1 35 ± 6.7 0.74
Testosterone (ng/dL) 32.3 ± 21.5 27.8 ± 14.8 0.81
CRP (mg/L) 3.34 ± 3.60 3.02 ± 1.64 0.74

Mean ± Standard deviation. Non-parametric Mann-Whitney test p ≤ 0.05.