Figure 2.

Increased functional connectivity of the somatosensory cortex in highly disabled MS patients. Patients with high disability display higher primary left somatosensory connectivity with the left prefrontal cortex (PF), premotor cortex (PM), secondary sensory cortex (S2) and right and left posterior associative sensory cortex (PAS) compared to patients with low disability and HC. In addition, stronger connectivity with the left supplementary motor area (SMA) was seen in highly disabled patients compared to HC. The stronger connectivity between these areas is reflected by edges between the bigger nodes in green. The blue dots reflect the remaining sensorimotor network regions.

L: left; R: right.