Table 2.
The mean local efficiency values of each sensorimotor region for each group.
| Sensorimotor regions | HC | LD | HD | p-values |
|---|---|---|---|---|
| Left prefrontal cortex | 0.95 (0.11) | 0.96 (0.12) | 1.00 (0.13) | 0.059 |
| Left supplementary motor area | 1.09 (0.16) | 1.11 (0.20) | 1.16 (0.28) | 0.391 |
| Left premotor cortex | 1.04 (0.15) | 1.07 (0.18) | 1.16 (0.28) a | 0.015 |
| Left primary motor cortex | 1.05 (0.14) | 1.08 (0.16) | 1.14 (0.20) | 0.099 |
| Left primary somatosensory cortex | 1.07 (0.12) | 1.09 (0.16) | 1.20 (0.23) a,b | 0.002 |
| Left secondary sensory cortex | 1.06 (0.12) | 1.08 (0.14) | 1.15 (0.24) | 0.051 |
| Left posterior associative sensory cortex | 1.07 (0.14) | 1.09 (0.16) | 1.16 (0.23) | 0.172 |
| Left thalamus | 1.08 (0.23) | 1.11 (0.24) | 1.20 (0.37) | 0.352 |
| Left caudate nucleus | 1.05 (0.21) | 1.03 (0.25) | 1.12 (0.29) | 0.272 |
| Left putamen | 1.07 (0.19) | 1.05 (0.22) | 1.14 (0.28) | 0.297 |
| Left pallidum | 0.96 (0.20) | 0.95 (0.20) | 1.08 (0.41) | 0.105 |
| Right prefrontal cortex | 0.95 (0.16) | 0.97 (0.12) | 1.01 (0.15) | 0.084 |
| Right supplementary motor area | 1.10 (0.17) | 1.12 (0.19) | 1.16 (0.24) | 0.556 |
| Right premotor cortex | 1.06 (0.15) | 1.07 (0.17) | 1.14 (0.23) | 0.269 |
| Right primary motor cortex | 1.05 (0.14) | 1.08 (0.16) | 1.13 (0.19) | 0.188 |
| Right primary somatosensory cortex | 1.08 (0.13) | 1.10 (0.17) | 1.18 (0.21) | 0.064 |
| Right secondary sensory cortex | 1.07 (0.15) | 1.07 (0.15) | 1.14 (0.20) | 0.395 |
| Right posterior associative sensory cortex | 1.07 (0.13) | 1.08 (0.17) | 1.15 (0.24) | 0.257 |
| Right thalamus | 1.08 (0.22) | 1.10 (0.25) | 1.20 (0.34) | 0.384 |
| Right caudate nucleus | 1.06 (0.20) | 1.06 (0.23) | 1.11 (0.36) | 0.747 |
| Right putamen | 1.07 (0.20) | 1.06 (0.24) | 1.14 (0.27) | 0.453 |
| Right pallidum | 0.95 (0.18) | 0.96 (0.22) | 1.10 (0.46) a,b | 0.033 |
| Cerebellum | 1.02 (0.20) | 1.05 (0.21) | 0.96 (0.23) | 0.095 |
HC: healthy controls; LD: patients with low disability; HD: patients with high disability.
General linear model was used to compare local efficiency differences between groups and main effects were significant for the left premotor cortex, left primary somatosensory cortex and right pallidum (in bold).
a
After post hoc Bonferroni correction, significant differences were found compared to healthy controls.
b
After post hoc Bonferroni correction, significant differences were found compared to patients with low disability.