Table 1.
Demographic data.
| Controls, n=16 | Patients, n=16 | t-Value/X2 | p-Value | |||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| Age | 43.62 | 12.57 | 46 | 12.29 | −0.54 | 0.593 ns |
| BMI | 24.61 | 4.24 | 30.48 | 5.24 | −3.48 | 0.002** |
| HRSD | 2.12 | 2.0 | 21.88 | 4.26 | −16.81 | <0.001*** |
| QIDS | 2 | 2.39 | 18,50 | 3.08 | −16.93 | <0.001*** |
| Smoking | 12% | 19% | – | 0.237 | 0.626 ns | |
| Sex female | 69% | – | 69% | – | 0 | 1 ns |
| HR (bpm) | 62.44 | 5.33 | 77.79 | 9.53 | −5.62 | <0.001*** |
| RMSSD (ms) | 69.64 | 20.5 | 38.88 | 14.34 | 4.96 | <0.001*** |
| Std. ACC | 0.05 | 0.01 | 0.03 | 0.01 | 6.39 | <0.001*** |
| Antidepressant medication | n | % | ||||
| SSRI/SNRI/SARI | – | – | 11 | 69% | – | – |
| TCA/TECA | – | – | 5 | 31% | – | – |
| Benzodiazepines/Atypical/Other | – | – | 14 | 88% | – | – |
| Unmedicated | 0 | 0% | ||||
Differences are indicated for healthy controls and patients, matched for sex and of similar age. For wearable data of patients, pre- and post-treatment phases are taken into account. BMI, body mass index; HRSD, Hamilton Ratings Scale for Depression; QIDS-SR, Quick Inventory of Depressive Symptomatology Self-Rated version; HR, heart rate at baseline; RMSSD, root mean square of successive differences at baseline; Std ACC, unfiltered standard deviation of the activity index. * P < 0.05; ** P < 0.01; *** P < 0.001; ns, not significant. Bold values indicate significant results.