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. 2021 Jul 29;11:706652. doi: 10.3389/fonc.2021.706652

Table 2.

Univariate analyses and multivariate analyses of meta-regression.

Covariate Univariate analyses Multivariate analyses
Moderators I2 (residual heterogeneity) Residual Heterogeneity Signif. Moderators I2 (residual heterogeneity) Residual Heterogeneity Signif.
OS
sample size p = 0.0082 42.51% p = 0.0081 ** p = 0.1990
Sample Source p < 0.0001 12.34% p = 0.2769 *** p = 0.0004 0.00% 0.7883 ***
Cutoff of TMB p = 0.0963 29.80% p = 0.21137 . p = 0.0911 .
PFS
sample size p = 0.0495 55.67% p < 0.0001 * p = 0.0273 *
Sample Source p = 0.0756 58.72% p < 0.0001 . p = 0.7556 44.82% 0.0163
Cutoff of TMB p = 0.4601 47.51% p = 0.0064 p = 0.3136

Signif. codes: ‘***’, 0.001; ‘**’, 0.01; ‘*’, 0.05; ‘.’, 0.1; ‘ ’, 1.