TABLE 2.

Biometric and echocardiographic parameters of the C57BL/6 experimental mice.

	Ctrl (n = 8)	STZ
		n = 8	A-10MG (n = 8)	A-20MG (n = 9)
HR, bpm	525 ± 79	489 ± 78	514 ± 54	527 ± 41
HW/BW, mg/g	5.78 ± 0.26	6.61 ± 0.36***	5.74 ± 0.34###	5.94 ± 0.23##
IVSD, mm	0.73 ± 0.04	0.75 ± 0.08	0.73 ± 0.03	0.70 ± 0.03
LVIDd, mm	2.23 ± 0.10	2.45 ± 0.06	2.17 ± 0.15#	2.16 ± 0.12##
IRT, ms	14.14 ± 2.03	24.5 ± 1.91***	16.67 ± 1.37	17.33 ± 2.18###
Tei index	0.70 ± 0.07	0.84 ± 0.14	0.73 ± 0.02	0.70 ± 0.02
EF%	82.03 ± 2.94	73.26 ± 1.45**	79.58 ± 2.11#	79.26 ± 1.86#
FS%	44.09 ± 2.37	36.85 ± 2.25**	43.36 ± 3.33#	42.99 ± 3.22#

Ctrl, control; HR, heart rate; HW/BW, heart weight/body weight; IVSD, diastole interventricular septal thickness; LVIDd, diastole left ventricle internal dimension; IRT, isovolumic relaxation time; EF%, ejection fraction %; FS%, fractional shortening %.

Data presented as Mean ± SD, ^∗∗p < 0.01, and^∗∗∗p < 0.001, compared to Ctrl group; ^#p < 0.05, ^##p < 0.01, and ^###p < 0.001, compared to STZ group.