Table 4.
Correlations between the levels of EVs and inflammatory parameters and the parameters of the global haemostatic assays.
| Parameters | CRP | ESR | OCP | OHP | OFP | Max Abs | CLT |
|---|---|---|---|---|---|---|---|
| PS+EVs | p = 0.048 r = 0.32 |
p = 0.009 r = 0.41 |
p = 0.013 r = 0.39 |
p = 0.001 r = 0.51 |
p = 0.006 r = –0.43 |
p = 0.001 r = 0.511 |
p = 0.002 r = 0.467 |
| PEVs (CD42a+) | p = 0.031 r = 0.34 |
p = 0.007 r = 0.42 |
p = 0.039 r = 0.33 |
p = 0.002 r = 0.47 |
p = 0.006 r = –0.43 |
p = 0.004 r = 0.441 |
p = 0.006 r = 0.426 |
| TF+EVs (CD142+) | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 |
| LEVs (CD45+) | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p = 0.024 r = 0.355 |
p = 0.049 r = 0.313 |
| MoEVs (CD14+) | p = 0.001 r = 0.51 |
p = 0.005 r = 0.44 |
p > 0.05 | p > 0.05 | p = 0.031 r = –0.34 |
p = 0.002 r = 0.484 |
p = 0.005 r = 0.439 |
| P-selectin (CD62P+) | p = 0.015 r = 0.38 |
p = 0.004 r = 0.47 |
p > 0.05 | p = 0.014 r = 0.39 |
p = 0.015 r = –0.38 |
p > 0.05 | p = 0.007 r = 0.420 |
| EEVs (CD144+) | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 |
| E-selectin (CD62E+) | p > 0.05 | p > 0.05 | p > 0.05 | p > 0.05 | p = 0.041 r = –0.32 |
p > 0.05 | p = 0.028 r = 0.349 |
EVs, extracellular vesicles; PS, phosphatidylserine; TF, tissue factor; PEVs, platelet-derived EVs; LEVs, leucocyte-derived EVs; MoEVs, monocyte-derived EVs; EEVs, endothelial EVs; OHP, Overall hemostasis potential; OCP, Overall coagulation potential; OFP, Overall fibrinolytic potential; Max Abs, increase in absorbance from baseline to maximum value.