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. 2021 Jun 2;164(1):148–160. doi: 10.1111/imm.13350

FIGURE 1.

FIGURE 1

Blocking CD11c on human MoDCs inhibited allogeneic CD4+ T‐cell proliferation and Th1 cell differentiation. (a, c, e) Representative flow cytometric analysis of human CD4+ CD69+ T‐cell (a), CD4+ IFN‐γ+ T‐cell (c) and CFSE‐labelled CD4+ T‐cell (e) percentages, cocultured with allogeneic MoDCs for 3 days pretreated with CD11c blocking antibody or CD11c control antibody. (b, d, f) Percentages of human CD4+ CD69+ T cells (b), CD4+ IFN‐γ+ T cells (d) and proliferative CD4+ T cells (f), cocultured with allogeneic MoDCs for 3 days pretreated with CD11c blocking antibody or CD11c control antibody. Results are presented as mean ± SD, *P < 0·05, **P < 0·01, ***P < 0·001, by paired‐samples t‐test (b, d, f)