FIGURE 5.

Reg3γ and its putative receptor Extl3’s expression kinetics in the spinal cord and intestinal tissues during experimental autoimmune encephalomyelitis (EAE) and in MS patient CSF cells (a) Spinal cord (SC) and small intestine (SI) tissues from naïve, 7‐ and 20‐day post‐immunization from EAE mice were collected, and real‐time qPCR was performed for Reg1α, Reg3γ and Extl3 (n = 3). (b) The cerebrospinal fluid (CSF) from MS patients or controls was spun, and the cell pellet was used for real‐time qPCR for EXTL1, EXTL3, REG1A, REG1B and REG3A (n = 5 for each group). (*) indicates p‐value <0·05