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TIME landscape and immune checkpoints profiles of RAIS in four cohorts. (A) The correlation analysis between RAIS and 28 immune cells infiltration abundance. (B) The distribution difference of activated CD4+/CD8+ T cells infiltration between the high-risk and low-risk groups. (C) Four heatmaps of 27 immune checkpoints profiles in high-risk and low-risk groups. *P < 0.05, **P < 0.01, ***P < 0.001.
