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. 2021 Jul 6;25(16):7840–7854. doi: 10.1111/jcmm.16698

FIGURE 6.

FIGURE 6

Up‐regulation of lipid metabolism and thermogenesis in visceral white adipose tissue of the M;G mice. (A) Relative tissue weight of the HFD‐fed mice at the age of 7‐8 mo. n = 6. (B) Photographs of eWAT, iWAT and BAT from control and M;G mice fed on HFD. Scale bar: 1 cm. (C) Histology of adipose from the HFD‐fed control and M;G mice. Scale bar: 50 μm. (D‐E) mRNA expression of indicated genes in eWAT from the HFD‐fed control and M;G mice. n = 6 control mice, n = 5 M;G mice. (F) mRNA expression of indicated genes in eWAT from the chow diet‐fed control and M;G mice. n = 5. (G) Mitochondrial respiration rates of eWAT of the chow diet‐fed mice using palmitoylcarnitine/malate (PC/Mal) as substrates. PC/Mal‐stimulated, ADP‐dependent and oligomycin‐induced respiration were shown. n = 5 control mice, n = 4 M;G mice. Values are means ± SEMs, *P < .05; **P < .01; ***P < .001 (t test).