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. 2021 Jun 25;25(16):8028–8038. doi: 10.1111/jcmm.16734

FIGURE 5.

FIGURE 5

Circ_0002984 regulates cell viability, migration and inflammation via targeting miR‐326‐3p in VSMCs incubated with ox‐LDL. A, The viability of VSMCs treated with 100 µg/mL ox‐LDL, ox‐LDL +circ_0002984‐OE or ox‐LDL +circ_0002984‐OE +miR‐326‐3p mimics was tested by CCK‐8 assay. B, C, The migration of VSMCs was evaluated by Transwell assay. Five visual fields were randomly selected to calculate the number of cells. D, E, IL‐6 and TNF‐α mRNA levels were determined by RT‐qPCR. F, G, Concentration of IL‐6 and TNF‐α was tested by ELISA assay. Compared with the control group, *P < 0.05