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. 2021 Jun 25;25(16):8028–8038. doi: 10.1111/jcmm.16734

FIGURE 6.

FIGURE 6

Circ_0002984 regulates VAMP3 via sponging miR‐326‐3p. A, The potential target sites between miR‐326‐3p and VAMP3. B, The luciferase activity of VAMP3 3'UTR WT and VAMP3 3'UTR MUT. C, D, VAMP3 mRNA expression in VSMCs indicated with different doses of ox‐LDL or 100 μg/mL ox‐LDL at different time. E, F, The expression of VAMP3 in VSMCs transfected with the miR‐370‐3p mimics or inhibitors. G, H, The expression of VAMP3 in VSMCs treated with 100 µg/mL ox‐LDL, ox‐LDL +circ_0002984‐OE or ox‐LDL +circ_0002984‐OE +miR‐326‐3p mimics. Compared with the control group, *P < 0.05