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Qingda granule (QDG) inhibits ERK signaling pathways induced by angiotensin (AngII). (A) Immunohistochemical staining of phospho-ERK (p-ERK) in the abdominal aorta (scale bar = 100 um) and its intensity (B) was analyzed. (C) Western blotting of p-ERK and ERK in primary VSMCs and intensity ratio of p-ERK and ERK (D) was analyzed. Data are presented as mean ± SD; n = 5 for in vivo study and n = 3 for in vitro study; *p < 0.05 vs. Control group, #p < 0.05 vs. AngII group.
