Table 3. Tumor Growth Inhibition and Survival Time Data of CT-26 Colorectal-Bearing BALB/c Mice (n = 5) after Different Treatment Modalities.
tumor
growth inhibition |
survival
time |
|||||
---|---|---|---|---|---|---|
treatment groups | median tumor volume (mm3) | mean growth inhibition rate (%) | P value | median life (day) | increase in life span (%) | P value |
control | 4394.01 | 22 | ||||
5-Fu | 2229.6 | 49.25 | <0.001 | 29 | 31.81 | 0.004 |
MNPs | 4144.45 | 7.9 | NS | 23 | 4.54 | NS |
5-Fu/MNPs | 766.51 | 82.55 | <0.001 | 35 | 59.09 | <0.001 |
AMF | 3580.07 | 18.52 | 0.019 | 26 | 18.18 | 0.017 |
5-Fu + AMF | 523.88 | 88.07 | <0.001 | 38 | 72.72 | <0.001 |
MNPs + AMF | 1276.93 | 70.93 | <0.001 | 32 | 45.45 | <0.001 |
5-Fu/MNPs + AMF | 285.08 | 93.51 | <0.001 | 42 | 90.9 | <0.001 |