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. 2021 Aug 11;25:291. doi: 10.1186/s13054-021-03715-1

Fig. 5.

Fig. 5

Variability in relation to initial levels. Plots of sample 1 levels versus the pair-wise Δ for each CSF parameter. Albumin, granulocytes, erythrocytes, and the LE ratio have been log-transformed in order to improve visualization. Cells show a clear heteroscedasticity potentially impacting diagnostics that is not seen for glucose and lactate, but to some extent for albumin. This suggests a heterogeneity of larger molecules in the sampled volumes. Δ: pair-wise difference