Table 3.

Univariate and multivariate Cox regression for clinical variables and the prognostic risk model in international validation group

Prognostic index	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
TCGA SKCM set (n = 92)
Age	1.021 (1.003–1.039)	0.022	1.015 (0.995–1.035)	0.148
Gender	0.837 (0.496–1.411)	0.504
Race	1.102 (0.15–8.089)	0.924
Pathological stage	1.406 (1.023–1.932)	0.035	0.745 (0.43–1.292)	0.295
Pathological M	47.619 (10.351–219.066)	< 0.001	21.963 (4.23–114.032)	< 0.001
Pathological N	1.407 (1.081–1.831)	0.011	1.68 (1.114–2.533)	0.013
Pathological T	1.319 (1.1–1.582)	0.003	1.324 (1.058–1.658)	0.014
Risk score	1.699 (1.118–2.582)	0.013	1.351 (1.112–1.631)	0.027

T, tumor; N, lymph node; HR, hazard ratio; CI, confidence intervals