. 2021 Aug 11;19:238. doi: 10.1186/s12957-021-02348-6

Table 3.

Results of multivariable analysis for CSS

	Non-adjusted^a	Adjust I^b	Adjust II^c
	HR (95% CI), P value	HR (95% CI), P value	HR (95% CI), P value
Postoperative capecitabine duration	0.90 (0.84, 0.97), 0.0043	0.90 (0.84, 0.97), 0.0076	0.89 (0.82, 0.96), 0.0035
0	1.0	1.0	1.0
≤ 12 weeks	0.48 (0.24, 0.99), 0.046	0.46 (0.21, 0.98), 0.045	0.37 (0.17, 0.82), 0.015
≤ 24 weeks	0.09 (0.01, 0.67), 0.018	0.09 (0.01, 0.69), 0.020	0.07 (0.01, 0.56), 0.012

Notes: ^aNon-adjusted model adjusted for: none

^bAdjust I adjust for: gender; age

^cAdjust II adjust for: gender; age; stage; CEA; CA199; CCI; histological type, and MMR status

Abbreviations: HR hazard ratio; CI confidence interval; CA carcinoma antigen; CEA carcinoembryonic antigen; MMR mismatch repair; CCI Charlson comorbidity index