TABLE 2.
Post‐mortem human hippocampal samples
| Group | No. | Clinical Diagnosis | Gender | Age | Amyloid | Braak | ApoE (Presence of ApoE alleles) |
|---|---|---|---|---|---|---|---|
| Controls | 1 | Nondemented control | M | 89 | 0 | 2 | Unknown |
| 2 | Nondemented control | F | 92 | 0 | 3 | 43 | |
| 3 | Nondemented control | F | 78 | A | 1 | 33 | |
| 4 | Nondemented control | F | 60 | 0 | 0 | 32 | |
| 5 | Nondemented control | F | 93 | 0 | 2 | 33 | |
| 6 | Nondemented control | F | 82 | A | 1 | 33 | |
| 7 | Nondemented control | M | 73 | A | 2 | 33 | |
| 8 | Nondemented control | F | 72 | A | 1 | 33 | |
| AD patients | 1 | Alzheimer's disease | F | 85 | C | 6 | 44 |
| 2 | Alzheimer's disease | M | 60 | C | 6 | 43 | |
| 3 | Alzheimer's disease | M | 84 | C | 6 | 43 | |
| 4 | Alzheimer's disease | M | 74 | C | 6 | 43 | |
| 5 | Alzheimer's disease | F | 61 | C | 6 | 44 | |
| 6 | Alzheimer's disease | F | 71 | C | 6 | 44 | |
| 7 | Alzheimer's disease | F | 91 | C | 6 | 42 | |
| 8 | Alzheimer's disease | M | 81 | C | 6 | 43 | |
| 9 | Alzheimer's disease | F | 88 | C | 6 | 43 | |
| 10 | Alzheimer's disease | F | 78 | C | 6 | 43 | |
| 11 | Alzheimer's disease | F | 90 | C | 6 | 44 | |
| 12 | Alzheimer's disease | M | 78 | C | 6 | 43 |
This table shows the characteristics of the human (control and AD) individuals whose brain tissues were analysed in this study. [Amyloid]: 0, absent; A, mild (basal frontal and temporal lobes); B, moderate (association neocortex and hippocampus); C, severe (primary cortices, subcortical nuclei and cerebellum).