. 2020 Dec 18;87(7):2807–2817. doi: 10.1111/bcp.14685

TABLE A1.

Beers and PROMPT criteria definition according to IADB database

PIM	Definition IADB
PIM	Beers for ≥ 65 years	PROMPT for 45–64 years
Antihistamines, first generation ‐ Avoid in Beers ‐ No first line for >7 days in PROMPT	R06AD01, N07CA52, N07CA02, R06AA04, R06AE03, R06AB03, N05BB01, R06AX17, R06AE05, R06AE55, R06AD08, R06AD02 Additional^a: See PROMPT definition	No first line: R06 first generation (see list ATC codes for Beers) at initiation, i.e. without R06 in the preceding 1 year, and > 7 days
Corticosteroids ‐ No long term without biphosponate in PROMPT	Additional^a: See PROMPT definition	H02A or H02B or M01BA > 3 months, without M05BA or M05BB in the same period
Tricyclic antidepressants, alone or in combination ‐ Avoid in Beers ‐ No first line in PROMPT	N06AA	N06AA, without N06 in the preceding 1 year
Benzodiazepines ‐ Avoid in Beers ‐ No long term in PROMPT	N05BA, N05CD Additional^a: See PROMPT definition	N05BA or N05CD > 4 weeks
Nonbenzodiazepine, benzodiazepine receptor agonist hypnotics ‐ Avoid in Beers ‐ No long term in PROMPT	N05CF Additional^a: See PROMPT definition	N05CF > 4 weeks
Strong opioids (e.g. buprenorphine, diamorphine, fentanyl, morphine, oxycodone) ‐ Not without laxatives in PROMPT	Additional^a: See PROMPT definition	N02A, without (A06AB or A06AC or A06AD) in overlapping period
Sulfonylureas, long‐acting ‐ Avoid in Beers and PROMPT	A10BB01, A10BB02	A10BB01, A10BB02
Proton pump inhibitors ‐ No long term (>8 weeks) in high dose	Additional^a: See PROMPT definition with additional exclusion of chronic oral corticosteroids or NSAIDS, for which long term use is appropriate in elderly	Omeprazol A02BC01 > 20 mg, >8 weeks Pantoprazol A02BC02 > 40 mg, >8 weeks Lansoprazol A02BC03 > 30 mg, >8 weeks Rabeprazole A02BC04 > 20 mg, >8 weeks Esomeprazole A02BC05 > 40 mg, >8 weeks
Stimulant laxatives ‐ No long term (>4 weeks), except for opioid induced constipation	Additional^a: See PROMPT definition	A06AB > 4 weeks, excluding when N02A overlapping in the same period
NSAIDs without PPI or misoprostol ‐ Avoid in Beers ‐ No long term (>3 months) in PROMPT	M01A or N02BA01 dosage >325 mg/day, excluding M01AE52, without A02BC or A02BB01 in the same period	M01A, excluding M01AE52, > 3 months, without A02BC or A02BB01 in the same period)
Dipyridamole, short acting ‐ Avoid in Beers ‐ No monotherapy in PROMPT	B01AC07, excluding extended‐release combination with B01AC06	B01AC07, without other B01A in same period
Theophylline ‐ No monotherapy in PROMPT	Additional^a: See PROMPT definition	R03DA04, without other R03 in the same period
Acetylsalicylic acid (aspirin) anti‐platelet ‐ Not >150 mg/day in PROMPT	Additional^a: See PROMPT definition	B01AC06, dosage >150 mg/day
Skeletal muscle relaxants ‐ Avoid in Beers	M03B	X
Antispasmodics, anticholinergic ‐ Avoid in Beers	A03A, A03B, A03C, A03D, A03E, A04AD	X
Oestrogens with or without progestins ‐ Avoid in Beers	G03CA, G03CB, G03CC, G03CX	X
Insulins, sliding scale ‐ Avoid in Beers	A10AB only, without other A10A in overlapping period	X
Disopyramide ‐ Avoid in Beers	C01BA03	X
Indomethacin ‐ Avoid in Beers	M01AB01	X
Digoxin ‐ No high dose in Beers	C01AA05, dosage >0.125 mg/day	X
Nifedipine, immediate release ‐ Avoid in Beers	C08CA05, immediate release	X
Pentazocine ‐ Avoid in Beers	N02AD01	X
Barbiturates ‐ Avoid in Beers	N05CA	X
Meprobamate ‐ Avoid in Beers	N05BC01	X
Ergoloid mesylate ‐ Avoid in Beers	C04AE01	X
Desiccated thyroid (thyroid extract) ‐ Avoid in Beers	H03AA05	X
Megestrol ‐ Avoid in Beers	G03AC05, G03DB02	X
Mineral oil, oral (wonderolie, castor oil) ‐ Avoid in Beers	A06AB05	X
Meperidine (pethidine) ‐ Avoid in Beers	N02AB02	X
Ketorolac ‐ Avoid in Beers	M01AB15	X

^{^a}

For the ≥ 65 years, additional criteria were defined using the PROMPT definition.

X: not included in PROMPT