Skip to main content
. 2020 Dec 10;100(4):409–420. doi: 10.1002/cyto.b.21979

FIGURE 4.

FIGURE 4

Characteristic features of APL cases on radar plots: The upper row shows typical features of a classic APL case: (1a) Leukemic cells with high SSC. (1b) First RP in AML1 panel highlights lack of monocytes (absence of the green cluster). (1c) Second RP in AML1 panel shows CD117+ leukemic cells (the bright pink cluster) and lack of CD34 expression (absence of the red cluster). (1d) RP in AML2 panel shows lack of HLA‐DR expression (absence of the cyan cluster). (1e) RP in AML3 panel highlights lack of CD2 expression on leukemic cells (absence of the dark blue cluster). The middle row shows characteristic features of a variant APL case: (2a) Intermediate SSC. (2b) Lack of monocytes. (2c) CD117+ (the bright pink cluster) and partial CD34 expression in the blast population (the red cluster). (2d) Lack of HLA‐DR expression. (2e) CD2 expression on leukemic cells (the dark blue cluster). The lower row shows a case of APL diagnosed as classic APL by morphology but with some immunophenotype features of vAPL. (3a) Intermediate SSC. (3b) Very few maturing granulocytes and lack of monocytes (3c) Partial CD34 expression (red) but negative CD117 on blast cells (the pale pink cluster). (3d) Lack of HLA‐DR expression. (3e) Partial CD2 expression on leukemic cells (the dark blue cluster). Axes of RPs are arranged as shown in Figure 2. Color legends are arranged based on descending color precedence in each panel with intent to highlight distinctive markers. AML, acute myeloid leukemia; APL, acute promyelocytic leukemia; RP, radar plot [Color figure can be viewed at wileyonlinelibrary.com]