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Melanogenesis inhibitory effects of PMCC polymeric micelles containing Glab in a reconstituted human skin model. (a) The test sample was incubated with the human skin model (MEL‐300A) for 14 d. The brightness of the skin surface was assayed. (b) Macroscopic views of a human skin model. (A) Placebo (O/W micelle without Glab). (B) placebo (PMCC micelle without Glab). (C) Control (O/W micelle). (D) PMCC micelle. Significant difference is indicated (**P<.01, ANOVA)
