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Diuretic (A) and haemodynamic (B, C) effects of pecavaptan and tolvaptan during continuous arginine vasopressin (AVP) infusion in anaesthetised heart failure dogs. All data are mean of n = 3 ± standard error of the mean. CO, cardiac output; i.v., intravenous; TPR, total peripheral resistance. *P < 0.05.
