TABLE 3.
Influence of CcpA‐HPr~P interaction on regulation and DNA binding of genes encoding carbohydrate transport systems of MGAS2221
| M5005 spy# | Putative transported carbohydrate | Transporter type | CcpA repressed vs. activated | HPr~P dependent vs. independent | Bound by CcpA | Bound by CcpAV301A |
|---|---|---|---|---|---|---|
| 0212‐0219 | Sialic acid | ABC | Repressed | Independent | Yes | No |
| 0475 | Β‐glucoside | PTS | Repressed | Semi‐dependent | No | No |
| 0521 | N‐acetylglucosamine | PTS | Repressed | Independent | No | No |
| 0662 | Fructose | PTS | Repressed | Fully ‐dependent | No | No |
| 0780‐0783 | Mannose/fructose | PTS | Repressed | Semi‐dependent | No | No |
| 1058‐1060 | Maltose | ABC | Repressed | Semi‐dependent | Yes | Yes |
| 1067‐1062 | Maltodextrin | ABC | Repressed | Semi‐dependent | Yes | Yes |
| 1083‐1079 | Cellobiose | PTS | Repressed | Semi‐dependent | Yes | Yes |
| 1310‐1308 | Unknown sugar | ABC | Repressed | Semi‐dependent | No | No |
| 1399‐1401 | Galactose | PTS | Repressed | Semi‐dependent | No | No |
| 1479‐1481 | Mannose | PTS | Repressed | Semi‐dependent | Yes | Yes |
| 1542 | Sucrose | PTS | Activated | Semi‐dependent | No | No |
| 1634‐1633 | Lactose | PTS | Activated | Fully ‐dependent | No | No |
| 1664‐1662 | Mannitol | PTS | Repressed | Semi‐dependent | No | No |
| 1692 | Maltose | PTS | Repressed | Independent | Yes | Yes |
| 1746‐1744 | Cellobiose | PTS | Repressed | Semi‐dependent | Yes | No |
| 1784 | Trehalose | PTS | Repressed | Semi‐Dependent | No | No |
Abbreviations: ABC, ATP binding cassette; PTS, phosphotransferase system;