Table 1.

COMPASS-31 score, domains, and additional items in post-COVID patients with and without neurological symptoms

	Neuro n = 97	Others n = 83	Significance
Age (y)	53 ± 14	49 ± 11	0.073
Females [n (%)]	67 (69.1)	60 (72.3)	0.743
COMPASS-31
Score [0–100]	20.7 (5.4–32.2)	14.2 (8.2–30.3)	0.002
> 13.25 [n (%)]	55 (56.7)	45 (55.4)	0.654
Orthostatic intolerance
Score [0–40]	12.0 (0.0–20.0)	0.0 (0.0–20.0)	< 0.001
> 0 [n (%)]	53 (54.6)	39 (47.0)	0.369
Vasomotor
Score [0–5]	0.0 (0.0–0.0)	0.0 (0.0–0.0)	0.226
> 0 [n (%)]	22 (22.7)	20 (24.1)	0.860
Secretomotor
Score [0–15]	2.0 (0.0–6.0)	2.1 (0.0–6.4)	0.227
> 0 [n (%)]	53 (54.6)	45 (54.2)	1.000
Gastrointestinal
Score [0–24]	3.0 (0.0–6.1)	4.5 (2.7–7.1)	< 0.001
> 0 [n (%)]	66 (68.0)	77 (92.8)	< 0.001
Urinary
Score [0–10]	0.0 (0.0–1.0)	0.0 (0.0–1.1)	< 0.001
> 0 [n (%)]	26 (26.8)	38 (45.8)	0.012
Pupillomotor
Score [0–6]	1.0 (0.0–2.0)	1.3 (0.3–2.3)	< 0.001
> 0 [n (%)]	59 (60.8)	64 (77.1)	0.024
Global autonomic symptoms [n (%)]	23 (23.7)	24 (28.9)	0.496
Environmental intolerance [n (%)]
Heat	17 (17.5)	23 (27.7)	0.109
Cold	33 (34.0)	34 (41.0)	0.356
Humid	8 (8.2)	20 (24.1)	0.004
Wind	4 (4.1)	9 (10.8)	0.093
Subj. thermal sensation [n (%)]
Heat	7 (7.2)	12 (14.5)	0.145
Cold	5 (5.2)	16 (19.3)	0.005
Sexual impairment [n (%)]	13 (13.4)	13 (15.7)	0.677

Means ± standard deviations, medians (25th–75th percentile) and proportions are reported