Table 4.
Odds ratios and 95% CI of the association between maternal serum Vitamin B12 (continuous, quintiles) and offspring ADHD
| (A) Vitamin B12 as a continuous variable | ||||||
|---|---|---|---|---|---|---|
| Case (N = 1026) | Control (N = 1026) | Association with maternal serum Vitamin B12 | ||||
| Maternal Vitamin B12 levels (pmol/L) | Median | Median | Odds ratio (unadjusted) 95% CI | p value | Odds ratio (adjusteda) 95% CI | p value |
| Log-transformed analysis | 4.50 | 4.52 | 0.96 (0.79–1.16) | 0.685 | 0.97 (0.79–1.18) | 0.759 |
| (B) As a categorical variable | ||||||
|---|---|---|---|---|---|---|
| Case (N = 1026) | Control (N = 1026) | Association with maternal serum Vitamin B12 | ||||
| Maternal Vitamin B12 (%) (pmol/L) | n (%) | n (%) | Odds ratio (unadjusted) 95% CI | p value | Odds ratio (adjusteda) 95% CI |
p value |
| Quintiles | ||||||
| < 20 (< 1.20) | 202 (19.68) | 202 (19.68) | 0.96 (0.73–1.26) | 0.771 | 0.96 (0.73–1.27) | 0.803 |
| 20–39 (1.20–2.38) | 219 (21.34) | 205 (19.98) | 1.02 (0.77–1.34) | 0.883 | 1.03 (0.78–1.37) | 0.802 |
| 40–59 (2.39–4.02) | 206 (20.07) | 205 (19.98) | 0.95 (0.72–1.26) | 0.758 | 0.98 (0.74–1.29) | 0.892 |
| 60–79 (4.03–7.09) | 184 (17.93) | 208 (20.27) | 0.84 (0.63–1.11) | 0.236 | 0.87 (0.65–1.16) | 0.360 |
| ≥ 80 (≥ 7.10) | 215 (20.95) | 206 (20.07) | Reference | Reference | ||
aAdjusted for maternal SES