Table A1.
parameters in active tuberculosis and community-acquired pneumonia and healthy control (Mean ± SD)
| Parameter | 1 | 2 | 3 | P | ||
|---|---|---|---|---|---|---|
| ATB (N = 88) | CAP (N = 78) | HC (N = 89) | 1 vs 2 | 1 vs 3 | 2 vs 3 | |
| WBC | 6.614 ± 2.224 | 8.175 ± 4.097 | 7.086 ± 2.746 | 0.0208 | Ns | Ns |
| NE% | 64.18 ± 9.191 | 71.31 ± 13.1 | 68.74 ± 12.46 | <0.0001 | 0.0075 | Ns |
| LY% | 20.7 ± 8.047 | 18.04 ± 13.6 | 21.23 ± 10.25 | 0.0302 | Ns | 0.0348 |
| MO% | 9.899 ± 3.522 | 7.945 ± 2.992 | 7.466 ± 2.579 | <0.0001 | <0.0001 | Ns |
| neutrophil CPD parameter | ||||||
| NMV | 144.2 ± 6.266 | 145.2 ± 7.995 | 145.7 ± 7.233 | Ns | Ns | Ns |
| NMV-SD | 20.32 ± 3.177 | 18.81 ± 2.633 | 17.85 ± 2.107 | 0.0059 | <0.0001 | Ns |
| NMC | 153.4 ± 2.645 | 139.8 ± 7.314 | 151.5 ± 3.526 | <0.0001 | 0.0003 | <0.0001 |
| NMC-SD | 9.042 ± 3.948 | 5.863 ± 1.734 | 5.536 ± 1.051 | <0.0001 | <0.0001 | Ns |
| N-MALS | 134.3 ± 5.684 | 128.99.347 | 136.6 ± 4.945 | 0.0006` | 0.0262 | <0.0001 |
| N-MALS-SD | 14.95 ± 5.118 | 12.73 ± 2.612 | 11.05 ± 1.572 | 0.0305 | <0.0001 | <0.0001 |
| N-UMALS | 137.8 ± 4.474 | 124.2 ± 11.22 | 136.3 ± 5.342 | <0.0001 | Ns | <0.0001 |
| N-UMALS-SD | 14.5 ± 4.385 | 16.82 ± 6.577 | 11.85 ± 1.68 | Ns | <0.0001 | <0.0001 |
| N-LMALS | 126.8 ± 9.128 | 127.3 ± 11.23 | 133 ± 6.441 | Ns | <0.0001 | 0.0016 |
| N-LMALS-SD | 19.16 ± 6.887 | 16.26 ± 4.386 | 14.05 ± 2.624 | 0.0008 | <0.0001 | 0.0004 |
| N-LALS | 155.2 ± 20.28 | 163.6 ± 18 | 170.9 ± 13.64 | 0.011 | <0.0001 | Ns |
| N-LALS-SD | 41.1 ± 6.712 | 34.27 ± 7.237 | 33.03 ± 6.652 | <0.0001 | <0.0001 | Ns |
| N-AL2 | 142.8 ± 3.893 | 140.7 ± 4.248 | 140.7 ± 5.399 | 0.0023 | 0.0048 | Ns |
| N-AL2-SD | 15.72 ± 4.343 | 15.73 ± 3.459 | 11.56 ± 1.843 | Ns | <0.0001 | <0.0001 |
| lymphocyte CPD parameter | ||||||
| LMV | 89.19 ± 4.457 | 89.1 ± 4.323 | 87.49 ± 3.956 | Ns | 0.0409 | Ns |
| LMV-SD | 17.55 ± 3.883 | 15.38 ± 2.686 | 15.31 ± 2.534 | 0.0011 | <0.0001 | Ns |
| LMC | 119.6 ± 3.204 | 111.7 ± 6.74 | 120.4 ± 3.021 | <0.0001 | Ns | <0.0001 |
| LMC-SD | 13.09 ± 2.558 | 9.642 ± 3.156 | 9.136 ± 1.923 | <0.0001 | <0.0001 | Ns |
| L-MALS | 61.27 ± 6.314 | 51.29 ± 13.23 | 64.53 ± 7.477 | <0.0001 | 0.0029 | <0.0001 |
| L-MALS-SD | 19.65 ± 2.614 | 17.42 ± 1.702 | 17.59 ± 1.808 | <0.0001 | <0.0001 | Ns |
| L-UMALS | 64.13 ± 8.007 | 44.54 ± 20.61 | 66 ± 9.197 | <0.0001 | Ns | <0.0001 |
| L-UMALS-SD | 21.91 ± 2.516 | 19.99 ± 2.875 | 19.41 ± 1.508 | <0.0001 | <0.0001 | Ns |
| L-LMALS | 54.03 ± 5.828 | 51.71 ± 7.47 | 58.43 ± 6.191 | Ns | <0.0001 | <0.0001 |
| L-LMALS-SD | 21.67 ± 2.818 | 20.19 ± 1.55 | 20.36 ± 1.664 | <0.0001 | <0.0001 | Ns |
| L-LALS | 39.85 ± 4.814 | 38.87 ± 2.894 | 37.65 ± 2.692 | Ns | <0.0001 | 0.0207 |
| L-LALS-SD | 14.94 ± 4.987 | 12.38 ± 1.96 | 11.69 ± 1.637 | <0.0001 | <0.0001 | Ns |
| L-AL2 | 75.76 ± 3.785 | 79.28 ± 3.407 | 75.23 ± 2.807 | <0.0001 | Ns | <0.0001 |
| L-AL2-SD | 12.78 ± 3.313 | 11.91 ± 2.354 | 10.94 ± 1.366 | 0.0223 | <0.0001 | 0.0195 |
| monocyte CPD parameter | ||||||
| MMV | 182.4 ± 11.35 | 166 ± 10.34 | 166.8 ± 7.935 | <0.0001 | <0.0001 | Ns |
| MMV-SD | 21.96 ± 2.533 | 20.51 ± 3.783 | 18.95 ± 3.034 | 0.0004 | <0.0001 | 0.0108 |
| MMC | 132.5 ± 2.389 | 119.4 ± 6.561 | 128.9 ± 3.146 | <0.0001 | <0.0001 | <0.0001 |
| MMC-SD | 7.266 ± 3.161 | 6.811 ± 2.953 | 6.087 ± 1.876 | 0.0216 | <0.0001 | Ns |
| M-MALS | 84.27 ± 3.353 | 74.19 ± 12.72 | 86.59 ± 5.088 | 0.0002 | 0.0002 | <0.0001 |
| M-MALS-SD | 10.91 ± 1.396 | 13.31 ± 2.944 | 11.74 ± 1.295 | <0.0001 | <0.0001 | 0.0012 |
| M-UMALS | 94.48 ± 5.368 | 76.29 ± 18.02 | 94.69 ± 6.135 | <0.0001 | Ns | <0.0001 |
| M-UMALS-SD | 11.87 ± 1.99 | 16.48 ± 4.544 | 12.73 ± 1.858 | <0.0001 | 0.0015 | <0.0001 |
| M-LMALS | 71.01 ± 2.845 | 67.46 ± 9.699 | 75.58 ± 5.032 | Ns | <0.0001 | <0.0001 |
| M-LMALS-SD | 14.07 ± 3.399 | 16.77 ± 3.094 | 14.73 ± 1.617 | <0.0001 | 0.0001 | <0.0001 |
| M-LALS | 81.4 ± 11.04 | 87.42 ± 14.32 | 90.58 ± 12.19 | 0.0001 | <0.0001 | Ns |
| M-LALS-SD | 23.19 ± 4.195 | 25.94 ± 3.796 | 26.43 ± 3.898 | <0.0001 | <0.0001 | Ns |
| M-AL2 | 131.6 ± 5.154 | 134.2 ± 4.587 | 131.3 ± 4.686 | 0.0003 | Ns | 0.0001 |
| M-AL2-SD | 12.45 ± 2.246 | 14.71 ± 3.824 | 12.64 ± 2.588 | <0.0001 | Ns | <0.0001 |
ATB: Active Tuberculosis, CAP: Community-acquired pneumonia, HC: Health control, WBC: White blood count, NE%: neutrophil percentage, LY％: lymphocyte percentage, MO%: monocyte percentage, NMV: Neutrophil mean volume,NMV-SD: Neutrophil mean volume standard deviation, NMC: Neutrophil mean conductivity, NMC-SD: Neutrophil mean conductivity standard deviation, N-MALS: Neutrophil medium angle light scatter, N-MALS-SD: Neutrophil medium angle light scatter standard deviation: N-UMALS: Neutrophil upper medium angle light scatter, N-UMALS-SD: Neutrophil upper medium angle light scatter standard deviation, N-LMALS: Neutrophil lower medium angle light scatter, N-LMALS-SD: Neutrophil lower medium angle light scatter standard deviation, N-LALS: Neutrophil lower angle light scatter, N-LALS-SD: Neutrophil lower angle light scatter standard deviation, N-AL2: Neutrophil axial light loss measurement, N-AL2-SD: Neutrophil axial light loss measurement standard deviation, LMV: Lymphocyte mean volume, LMV-SD: Lymphocyte mean volume standard deviation, LMC: Lymphocyte mean conductivity,LMC-SD: Lymphocyte mean conductivity standard deviation, L-UMALS:Lymphocyte upper median angle light scatter, L-UMALS-SD: Lymphocyte upper median angle light scatter standard deviation, L-MALS: Lymphocyte medium angle light scatter, L-MALS-SD: Lymphocyte medium angle light scatter standard deviation, L-LMALS: Lymphocyte lower median angle light scatter, L-LMALS-SD: Lymphocyte lower median angle light scatter standard deviation, L-LALS: Lymphocyte lower angle light scatter, L-LALS-SD: Lymphocyte lower angle light scatter standard deviation, L-AL2: Lymphocyte axial light loss measurement, L-AL2-SD: Lymphocyte axial light loss measurement standard deviation, MMV: Monocyte mean volume, MMV-SD: Monocyte mean volume standard deviation, MMC: Monocyte mean conductivity, MMC-SD: Monocyte mean conductivity standard deviation, M-UMALS: Monocyte upper median angle light scatter, M-UMALS-SD: Monocyte upper median angle light scatter standard deviation, M-MALS: Monocyte medium angle light scatter, M-MALS-SD: Monocyte medium angle light scatter standard deviation, M-LMALS: Monocyte lower median angle light scatter, M-LMALS-SD: Monocyte lower median angle light scatter standard deviation, M-LALS: Monocyte lower angle light scatter, M-LALS-SD: Monocyte lower angle light scatter standard deviation, M-AL2: Monocyte axial light loss measurement, M-AL2-SD: Monocyte axial light loss measurement standard deviation.