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. Author manuscript; available in PMC: 2022 Jul 22.
Published in final edited form as: Cell. 2021 Jun 14;184(15):4090–4104.e15. doi: 10.1016/j.cell.2021.05.013

Figure 7: Genes associated with periodontal disease susceptibility, microbe and damage sensing in the oral mucosa.

Figure 7:

A. Dot plot depicting the normalized and scaled average expression of genes and percentage of expressing cells for genes associated with Mendelian forms of periodontitis (left) and genes identified by GWAS to be associated with periodontitis (right). B. Summary of select pattern recognition receptors and damage-associated molecular pattern and associated receptors expression in buccal and gingival healthy mucosa (top) and expression in gingival health and periodontitis (bottom). Expression is shown by major tissue type (Endothelial, Fibroblast, Epithelial, Immune). A solid white border indicates statistical significance and the tissue that had higher expression. Significance determined by non-parametric Wilcoxon rank sum test. See also Table S7, Figure S7.