Skip to main content
. 2021 May 4;16(14):2206–2210. doi: 10.1002/cmdc.202100113

Table 1.

Measured molecular masses of the protein species, including ternary complexes, detected from 9 μM Brd4B1 or Brd4B2, 9 μM VCB and 7.8 μM GNE‐987.

Brd4 Bromodomain

Measured MW [Da]

Corresponding Species

Expected MW [Da]

Brd4B1

18814.0

Apo‐Brd4B1

18814.4

19040.0

Biotinylated Apo‐Brd4B1

19911.7

Holo‐Brd4B1

19910.7

20135.6

Biotinylated Holo‐Brd4B1

45412.9

Holo‐VCB

45412.7

64229.7

Ternary complex

64227.1

64455.5

Ternary complex containing biotinylated Brd4B1

Brd4B2

17386.9

Apo‐Brd4B2

17386.8

18482.4

Holo‐Brd4B2

18483.1

44317.2

Apo‐VCB

44316.4

45413.0

Holo‐VCB

45412.7

62799.4

Ternary complex

62799.5