Table 2B.
Macroscopic morphology outcomes meta‐analysis
| Outcome measure | Event rate/mean | 95% CI | I 2 | No. of comparisons | No. of articles | No. of animals |
|---|---|---|---|---|---|---|
|
Contraction ‐ PP vs. PP hybrid Sensitivity analysis |
32.7%a 30.3% vs. 32.1% 31.8% |
27.8 to 37.7 NS 26.9 to 36.7 |
90.1% | 29 | 8 | 174 |
| Degradation | 40.1%b | 23.9 to 58.8 | 36.5% | 15 | 5 | 68 |
|
Erosion ‐ Short vs. long |
11.6%b 12.1% vs. 11.1% |
6.8 to 19.0 NS |
0% | 24 | 4 | 95 |
|
Exposure ‐ Ewe vs. rabbit ‐ Rabbit vs. rat ‐ Ewe vs. rat ‐ PP vs. PP hybrid ‐ PP vs. biological ‐ PP vs. other ‐ PP hybrid vs. biological ‐ PP hybrid vs. other ‐ biological vs. other ‐ Short vs. long ‐ TA vs. TV |
20.1%b 25.5% vs. 23.0% 23.0% vs. 10.5% 25.5% vs. 10.5% 24.2% vs. 19.3% 24.2% vs. 14.3% 24.2% vs. 16.1% 19.3% vs. 14.3% 19.3% vs. 16.1% 14.3% vs. 16.1% 17.1% vs. 21.2% 16.8% vs. 20.4% |
16.8 to 24.0 NS p = 0.03 p < 0.01 NS NS NS NS NS NS NS NS |
0% | 114 | 25 | 584 |
| Extrusion | 26.0%b | 13.9 to 43.3 | 27.3% | 13 | 3 | 65 |
|
Implant retrieval ‐ PP vs. biological |
75.3%b 85.3% vs. 70.4% |
65.0 to 83.3 NS |
13.6% | 17 | 5 | 133 |
Note: Only subgroup analysis is shown which meets the requirements for subgroup analysis: ≥3 comparisons from ≥3 articles. See Supplementary file 4 for all subgroups per outcome measure, including CI of the above subgroup analysis.
Abbreviations: CI, confidence interval; I 2, heterogeneity; N, number; NS, nonsignificant; PP, polypropylene; TA, transabdominal; TV, transvaginal; vs., versus.
Mean value.
Event rate.