TABLE 1.

Summary of published cases with Nexilin dilated cardiomyopathy

Number	Author	Sex	Age at onset	DNA sequence change	Amino acid change	Clinical outcome	Remark
Homozygous
1	Patient 2	Female	Fetal	1174C > T	R392*	Died after 2 weeks
2	Al‐Hassnan et al.	?	1 month	1582‐1584del	GAA528del	Severe DCM	Sibling of patient 3
3		?	?	1582‐1584del	GAA528del	Severe DCM	Sibling of patient 2
Heterozygous
4	Kean et al.	Male	2 months	1723G > T	E575X	Severe DCM, improved later, in good clinical condition at 21 years	Twin of patient 5, additional SCN5A mutation
5		Male	2 months	1723G > T	E575X	Mildly reduced LV systolic function at 21 years	Twin of patient 4, additional SCN5A mutation
6	Patient 1	Male	3 months	1949_1951del	G650del	Severe DCM, improved later, in good clinical condition at 11 years
7	Klauke et al.	Male	5 years	1955A > G	Y652C	Severe DCM, ventricular assist device implantation at 22 years
8	Hassel et al.	Female	35 years	1948‐1950del	G650del	DCM, NYHA I
9		Female	40 years	1955A > G	Y652C	Severe DCM, NYHA II
10		Female	49 years	1948‐1950del	G650del	Severe DCM, NYHA III
11		Male	51 years	1831C > A	P611T	Severe DCM, NYHA III
12		Male	51 years	1948‐1950del	G650del	Severe DCM, NYHA II
13		Male	52 years	1948‐1950del	G650del	Severe DCM, NYHA II
14		Male	56 years	1948‐1950del	G650del	Severe DCM, NYHA II
15		Female	58 years	1955A > G	Y652C	Severe DCM, received heart transplantation
16		Female	65 years	1948‐1950del	G650del	Severe DCM, NYHA II
17	Haas et al.	Male	?	1174C > T	R392*	?

Abbreviation: DCM, dilated cardiomyopathy.