TABLE 1.

Study design and group assignments for prenatal developmental toxicity studies with ADBAC and DDAC in rats and rabbits

Test species	Group number	Treatment	Target dosage level (mg/kg/day)	Nominalconcentration (mg/ml)	Dose volume (ml/kg)	No. females
CD rats	1	Vehicle controla	0	0	5	25
	2	ADBAC	10	2.0	5	25
	3	ADBAC	30	6.0	5	25
	4	ADBAC	100	20.0	5	25
New Zealand White rabbits	1	Vehicle controla	0	0	2	16
	2	ADBAC	1	0.5	2	16
	3	ADBAC	3	1.5	2	16
	4	ADBAC	9	4.5	2	16
CD rats	1	Vehicle controla	0	0	5	25
	2	DDAC	1	0.2	5	25
	3	DDAC	10	2.0	5	25
	4	DDAC	20	4.0	5	25
New Zealand White Rabbits	1	Vehicle controla	0	0	2	16
	2	DDAC	1	0.5	2	16
	3	DDAC	3	1.5	2	16
	4	DDAC	10	5.0	2	16

^a The vehicle was deionized (Milli‐Q) water.

Abbreviations: ADBAC, alkyl dimethyl benzyl ammonium chloride; DDAC, didecyl dimethyl ammonium chloride.