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. 2021 Mar 23;60(29):15705–15723. doi: 10.1002/anie.202016575

Scheme 1.

Scheme 1

De novo synthesis of edge‐ and spiro‐fused pseudo‐NPs. a–c) Synthesis of edge‐fused pseudo‐NPs, including a) pyrano‐furo‐pyridones 2122 and 2425, by Pd‐ or quinine‐catalysed cascades; b) indomorphans 26, by Fischer indolisations; c) isoindolinones 32, by a mesoporous silica nanoparticle‐catalysed multi‐component reaction. d) Synthesis of spiro‐fused indiridoids 35 by an AuI‐catalysed cascade.