Table 3.

Features of the 13 chemicals included in the EDC mixture.

Substance	Function	AA/E	Dose ($\mathrm{\mu }\mathrm{g}/\mathrm{kg}/\mathrm{d}$)	NOAEL (mg/kg/d)	LOAEL (mg/kg/d)	References
Di-n-butyl phthalate	Plasticizer	AA	10	50	100	Mylchreest et al. 2000
Di(2-ethylexyl) phthalate	Plasticizer	AA	20	3	10	Christiansen et al. 2010
Bisphenol A	Plasticizer	AA/E	1.5	5	1.2	EFSA 2019; Kang et al. 2002; Salian et al. 2009
Vinclozolin	Dicarboximide fungicide	AA	9	5	10	Hass et al. 2007
Procymidon	Dicarboximide fungicide	AA	15	10	25	Hass et al. 2007
Prochrloraz	Imdazome fungicide	AA	14	5	10	Christiansen et al. 2009
Linuron	Urea-based herbicide	AA	0.6	25	50	McIntyre et al. 2001
Epoxinaxole	Triazole fungicide	AA	10	15	—	Taxvig et al. 2007
4-Methyl-benzylidene camphor	UV-filter	E	60	0.7	7	Durrer et al. 2007
Octyl methoxycinnamate	UV-filter	E	120	—	500	Cousins et al. 2002
p,p′-DDE	Metabolite of the insecticide DDT	AA/E	1	—	10	You et al. 1998
Butylparaben	Antifungal and antibacterial preservative	AA	60	—	100	Kang et al. 2002
Acetaminophen	Analgesic and antipyretic	AA	800	—	350	Hass et al. 2010

Note: —, no data available; AA, antiandrogenic; E, estrogenic; NOAEL, no observed adverse effect level; LOAEL, lowest observed adverse effect level; p,p′-DDE, dichlorodiphenyldichloroethylene; UV, ultraviolet.